Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| BRCA | rs115767227 | chr20:30506052 | A/G | 4.02E-14 | 1018 | 21.3 | 23.73 | 8.5 | KM Plot |
| BRCA | rs11579485 | chr1:41479917 | G/A | 1.72E-5 | 1021 | 21.83 | 21.17 | 11.2 | KM Plot |
| BRCA | rs116408748 | chr18:44702227 | A/C | 3.94E-6 | 1025 | 21.63 | 21.58 | 18.23 | KM Plot |
| BRCA | rs116869811 | chr7:54787365 | C/T | 8.43E-6 | 1026 | 21.43 | 25.13 | 3.97 | KM Plot |
| BRCA | rs11697717 | chr20:2771921 | A/G | 4.2E-5 | 1028 | 21.93 | 21 | 15.48 | KM Plot |
| BRCA | rs11698364 | chr20:2773294 | A/G | 4.0E-6 | 1015 | 21.97 | 21.08 | 10.82 | KM Plot |
| BRCA | rs117007319 | chr21:48065335 | G/A | 2.18E-5 | 1020 | 21.98 | 17.67 | 19.17 | KM Plot |
| BRCA | rs117165158 | chr7:54807344 | C/T | 8.52E-6 | 1024 | 21.43 | 24.9 | 8.07 | KM Plot |
| BRCA | rs11724349 | chr4:169267813 | T/C | 1.43E-5 | 1015 | 21.62 | 21.68 | 14.1 | KM Plot |
| BRCA | rs117892907 | chr7:54773329 | C/T | 7.71E-6 | 1025 | 21.43 | 26.17 | 3.97 | KM Plot |
| BRCA | rs11865221 | chr16:60800955 | C/T | 1.1E-8 | 1028 | 18.27 | 20.67 | 21.73 | KM Plot |
| BRCA | rs11906212 | chr20:30516266 | C/T | 3.46E-14 | 1024 | 21.27 | 23.73 | 8.5 | KM Plot |
| BRCA | rs11906890 | chr20:30492703 | G/A | 3.19E-14 | 1024 | 21.33 | 23.6 | 8.5 | KM Plot |
| BRCA | rs11907654 | chr20:30512051 | A/G | 5.1E-14 | 1019 | 21.3 | 23.8 | 8.5 | KM Plot |
| BRCA | rs11952442 | chr5:147407980 | C/A | 5.2E-5 | 1027 | 22.03 | 18.35 | 20.87 | KM Plot |